Frontier Fertility in the U.S. (1): Ovarian Rejuvenation Explained

A clear, balanced explainer of ovarian rejuvenation—what it is, who it’s for, how PRP, stem cells, and mitochondrial transfer work, plus costs, risks, and what to ask before you try.

PublishedOctober 18, 2025

Last UpdatedOctober 18, 2025

Even when the ovaries are thought to have ‘stopped,’ technology is beginning to reopen possibilities. Ovarian rejuvenation aims to restore or improve ovarian function. Candidates include people with diminished ovarian reserve, those diagnosed with POI, or individuals in peri/post-menopause who still hope to conceive with their own eggs. It remains experimental, but it adds another option where there used to be none.

1) What is ovarian rejuvenation?

2) Three approaches on the frontier

3) What studies show so far

4) Practical cautions today

5) A clinician at the frontier: Dr. Zaher Merhi

6) Before you try, align on goals

7) Bottom line — understanding turns hope into action

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